Learn about MS, how it affects the body, treatment options, and more.
The Effects of MS on the Body’s Systems
Nerves send messages to and from the brain, allowing the body and brain to function. They are coated by a protective layer called myelin.
Multiple sclerosis results when the immune system attacks the myelin, and the nerves become damaged. When the nerves are damaged, they can no longer effectively communicate with the brain, leading to challenges that impact different body systems.
The most common MS symptoms affect:
Eyes: Blurred vision, double vision, vision loss, changes in seeing colors, and painArms, legs, hands, and feet: Muscle weakness, numbness, prickling, or pins and needlesGeneral body: Difficulty with energy, standing, walking, moving, balance, or coordination
Nervous System
The nervous system includes the brain, spinal cord, and nerves, and is responsible for communication between the body and the brain.
MS affects the nervous system by attacking the layer of myelin that insulates nerves and changes how the nerves send messages to the brain, leading to different results.
Some examples of how MS affects the nervous system are:
Neuropathic pain: When MS damages the nervous system, it may result in pain, tightness, burning, or a pins-and-needles sensation. Vision: The optic nerve is part of the nervous system and sends messages between the eyes and brain. MS optic nerve damage can lead to vision loss, eye pain, seeing flashes of light, and other vision changes. Sensations: MS nerve damage can change how messages are sent to the brain from all over the body, causing sensations such as numbness and tingling. Mental health: Many people with MS experience anxiety or depression, mood swings, and other mental health changes. Cognitive function: The brain is part of the nervous system. People with MS may experience difficulties remembering, concentrating, solving problems, and thinking-related symptoms.
Musculoskeletal System
The musculoskeletal system includes the bones, muscles, and the tissues that connect them such as tendons and ligaments.
MS can damage nerves that work with the musculoskeletal system, leading to musculoskeletal symptoms, including:
Weakness: Muscles may become weak. Spasms: Muscles may become very tightly squeezed. Spasticity: Muscles may become very stiff and hard to move. Pain: People with MS may experience muscle and joint pain and difficulty with mobility.
Immune System
The immune system includes organs, cells, and proteins such as white blood cells, bone marrow, and lymph nodes.
MS is an autoimmune disease, meaning the immune system works improperly and attacks healthy cells. One of the treatments for MS suppresses the immune system to disrupt this damaging process. A side effect of this treatment is that the immune system is weakened and is less effective at protecting the body from illness.
Digestive System
The digestive system includes the liver, pancreas, gallbladder, and organs that make up the gastrointestinal, or GI, tract, including the stomach and intestines.
MS can affect the digestive system and cause challenges, such as:
Constipation, or difficulty passing stool, may occur because nerve damage can prevent muscles from moving waste through the body. Dysphagia, or difficulty swallowing, may occur with MS due to nerve damage affecting the coordination of the muscles in the mouth and throat. Heartburn occurs when stomach acid enters the esophagus and irritates the tissue there. People with MS experience heartburn when nerve damage interferes with the muscle that prevents acid from flowing in the wrong direction.
Reproductive System
The reproductive system includes organs needed to make babies.
The female reproductive system includes:
Cervix Fallopian tubes Ovaries Uterus Vagina
The male reproductive system includes:
Penis Prostate Testes
Men and women have different reproductive organs, so MS affects them differently. For example, men with multiple sclerosis may experience erectile dysfunction. Women with multiple sclerosis may experience MS symptoms that worsen before their period and during postpartum (after having a baby) or menopause.
Circulatory System
The circulatory system includes the heart, blood vessels, and blood. The lymphatic system is sometimes considered part of the circulatory system and includes bone marrow, white blood cells, lymph nodes, and organs such as the thymus gland.
The link between multiple sclerosis and the circulatory system is not fully understood. However, people with MS are at an increased risk of some circulatory conditions, including:
Heart failure - when the heart is no longer able to pump enough blood through the body Ischemic heart disease (IHD) or coronary artery disease (CAD) - when a substance called plaque blocks or prevents blood from flowing to the heart Stroke - when blood is unable to reach the brain
MS Symptoms
MS is an autoimmune disease affecting the nervous system, meaning symptoms can impact the entire body. They are unpredictable, can change over time, and differ for everyone.
MS Treatment
Multiple sclerosis is a lifelong condition. Medications and treatment options are available to manage the disease, prevent it from progressing, and relieve symptoms.
Bladder problems (e. g. , unable to control) Brain function difficulties Depression Dysesthesia (squeezing sensation) Fatigue Pain Sensations (e. g. , numbness, tingling) Spasticity (very tight, stiff muscles) Vision changes Walking (gait) challenges
Treatment options differ depending on the person, their symptoms, and how active the disease is at the time. MS can shift between active phases with increased symptoms called flare-ups and less active or inactive phases with decreased or no symptoms called remission.
Treatment options for multiple sclerosis include:
Steroids - used on a short-term basis for flare-ups or phases of active disease Preventive therapies - used to prevent flare-ups, reduce flare-up severity, and prevent the disease from getting worse Symptom management - options that vary depending on the person and their symptoms
In addition to medications for MS, behavior and lifestyle changes may improve symptoms. People with MS who do not smoke or who quit smoking, exercise regularly, and eat healthy foods tend to experience fewer flare-ups and less severe symptoms and may live longer.
Summary
Multiple sclerosis (MS) is a serious, lifelong medical condition when the immune system attacks the nerves in the brain and spinal cord, inhibiting proper communication between the body and the brain. Because of this, people with MS can experience various symptoms. Fortunately, symptoms are treatable with medications and lifestyle changes, and people with MS can live long, happy lives.
A Word From Verywell
Living with multiple sclerosis can be challenging. You may experience both physical and psychological symptoms, as well as social and lifestyle challenges. However, this condition is treatable. Reach out to a healthcare provider for support.
